MASP INHIBITORY COMPOUNDS AND USES THEREOF

The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases...

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Bibliographische Detailangaben
Hauptverfasser: TERSTEEGEN, Adrian, NEUBAUER, Thomas, ZUBOV, Dmitry, GLATZ, Marie, DREHER, Jan, BAUMANN, Lars, POETHKO, Thorsten, BIERER, Donald, TERJUNG, Carsten, FLAMME, Ingo, HOLTON, Simon, QIU, Yibo, XIONG, Jiancheng, JUHL, Cathleen
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.