A METHOD OF GENERATION OF PHARMACEUTICAL SUBSTANCES INTO AN AEROSOL

Invention relates to the methods of obtaining of a medical aerosol. Object - development of a higher efficient method of drug generation into an aerosol solved via generation of a drug into an aerosol comprising supplying of heated air to the initial drug substance presented in a form of a multilayer tablet and evaporation of the initial drug substance followed by nucleation of the obtained supersaturated vapor and condensational growth of the formed aerosol particles and delivery of the obtained aerosol to patient's lungs. According to the method, the initial drug substance is prepared in the form of a multilayer, for example, a three-layer tablet, the upper and lower layers of which are formed of a drug and the middle layer is compressed cellulose, and during the aerosol generation the adhesive properties of which allow retaining the drug which was originally not only in the solid state, but also in the liquid state, or transitioned from solid to liquid state as a result of heating. The positive effect of the proposed method is achieved as a result of using the initial drug substance in a form of a multilayer tablet, which allows to efficiently evaporate and condensate a wide range of drugs that are both in solid and liquid state, including those that experience melting during heating. Advantages: precise dosing of the amount of drug transferred to aerosol; allow increase the efficiency of the conversion of drugs initial substance into an aerosol.