SCN9A ANTISENSE PAIN KILLER

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 02 August 2018 (02.08.2018) WI P0 I PCT omit VIII °nolo oil! iflo oimIE (10) International Publication Number WO 2018/138585 Al (51) International Patent Classification: C07K 14/00 (2006.01) C12N 15/113 (2010.01) (21) International Application Number: PCT/IB2018/000160 (22) International Filing Date: 23 January 2018 (23.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/449,738 24 January 2017 (24.01.2017) US (71) Applicant: OLIPASS CORPORATION [KR/KR]; 20th Floor, Ace Dongbaek Tower, 16 Beon-gil, 16-4 Dongbaek Jungang-ro, Giheung-gu, Yongin-si, Gyeonggi-do 17105 (KR). (72) Inventors: CHUNG, Shin; Apt. 103-3703, 527 Beon- gil 80, 527 Beon-gil 80, Dongbaek Jukjeondae-ro, Gi- heung-gu, Yongin-si, Gyeonggi-do 16990 (KR). JUNG, Daram; The Sharp Central-city 1406-1502, 19 Dongtan- daerosibeom-gil, Hwaseong-si, Gyeonggi-do (KR). CHO, Bongjun; 316-1102 Ssangyong Apt. 20, Jungbudae-ro, 788 Beon-gil, Giheung-gu, Yongin-si, Gyeonggi-do 17077 (KR). JANG, Kangwon; Apt. 1701-1702, Dongbaek8-ro 9, Giheung-gu, Yongin-si, Gyeonggi-do 16998 (KR). JEON, Hyun Ju; 105 Dong 1301 Ho, 62-28, Eojeong-ro, Gihe- ung-gu, Yongin-si, Gyeonggi-do (KR). BAE, Jinyoung; 3rd Floor 302, Pyeongchonl-ro 8beon-gil 5-19, Gihe- ung-gu, Yongin-si, Gyeonggi-do (KR). BAE, Taeyeon; 201 Ho, 31, Pyeongchon 3-ro, Giheung-gu, Yongin-si, Gyeonggi-do 17001 (KR). JEON, Yeasel; 506, Hou-star, 98-32, Dongbaekjukjeon-daero, 527 Beon-gil, Giheung-gu, Yongin-si, Gyeonggi-do (KR). LEE, Jun Yeon; Apt. #201-706, 33, Yeonwon-ro 42beon-gil, Giheung-gu, Yon- gin-si, Gyeonggi-do (KR). PARK, Sun Hwa; 717-701 SK View Apt. 27-7, Baegot 3-ro, Siheung-si, Gyeonggi-do (KR). AN, Dan Bi; Apt. # C-608, 283, Dongbaekjun- gang-ro, Giheung-gu, Yongin-si, Gyeonggi-do (KR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT,