AZAINDOLE DERIVATIVES WHICH ACT AS PI3K INHIBITORS

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which...

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Bibliographische Detailangaben
Hauptverfasser: WALLACE, MICHAEL B, CHANG, EDCON, NOTZ, WOLFGANG REINHARD LUDWIG
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with PI3Kδ.