LIVE VIRUS HAVING A BANK OF DENGUE VIRUS ATTENUATED STRAINS, AND A DENGUE VACCINE CONTAINING SAME AS ANTIGENS

LIVE VIRUS HAVING A BANK OF DENGUE VIRUS ATTENUATED STRAINS, AND A DENGUE VACCINE CONTAINING SAME AS ANTIGENS

A highly safe dengue vaccine was invented that induced a neutralizing antibody response against all of the four serotypes of dengue virus without developing more than a fixed level of viremia with single administration. A tetravalent dengue virus formulation is provided that is excellent in both eff...

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Hauptverfasser: YAMAORI, Susumu, ABE, Motoharu, SHINMURA, Yasuhiko, TAKAGI, Shota, MARUNO, Shinichi, HAYASHI, Yasuhisa, UCHIDA, Naomi, SONODA, Kengo, KOMURA, Fusae, FUKUDA, Aki, KAMEYAMA, Kazuhisa, YOSHIMURA, Masaya
Format: Patent
Sprache:eng
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Zusammenfassung:A highly safe dengue vaccine was invented that induced a neutralizing antibody response against all of the four serotypes of dengue virus without developing more than a fixed level of viremia with single administration. A tetravalent dengue virus formulation is provided that is excellent in both efficacy (neutralizing antibody response) and safety (viremia).