Enzymatic Omega-Oxidation And Omega-Amination Of Fatty Acids

Enzymatic Omega-Oxidation And Omega-Amination Of Fatty Acids

Oxidizing fatty acid or its ester (I), comprises (a) contacting (I) with cytochrome P450-monooxygenase of cytochrome P153 (CYP153) family in presence of molecular oxygen and NADPH. Oxidizing fatty acid or its ester of formula (H 3C-(CH 2) n-COOR) (I), comprises (a) contacting (I) with cytochrome P45...

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Bibliographische Detailangaben
Hauptverfasser: HÄGER, HARALD, HAUBERG, MICHAELA, HENNEMANN, HANS-GEORG, PFEFFER, JAN, CHRISTOPH, WESSEL, MIRJA, HAAS, THOMAS, SCHAFFER, STEFFEN
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Oxidizing fatty acid or its ester (I), comprises (a) contacting (I) with cytochrome P450-monooxygenase of cytochrome P153 (CYP153) family in presence of molecular oxygen and NADPH. Oxidizing fatty acid or its ester of formula (H 3C-(CH 2) n-COOR) (I), comprises (a) contacting (I) with cytochrome P450-monooxygenase of cytochrome P153 (CYP153) family in presence of molecular oxygen and NADPH. R : H, CH 3, ethyl, propyl or butyl; and n : 0-30, preferably 6-24. An independent claim is also included for a whole-cell catalyst expressing a recombinant cytochrome P450 monooxygenase, a recombinant alcohol dehydrogenase, a recombinant transaminase and optionally at least one recombinant enzyme, preferably alanine dehydrogenase, ferredoxin or ferredoxin reductase.