FORFARANDE FOR FRAMSTELLNING AV PROSTAGLANDINER

1456838 Silylated prostaglandins PFIZER Inc 8 Nov 1973 [8 Nov 1972] 51997/73 Heading C3S [Also in Division C2] N - Methansulphonyl - 15 - (5,6 - dimethoxy- 2 - indanyl) - 9α,11α,15# - tris - (dimethylisopropylsilyloxy) - 16,17,18,19,20 - pentanor - 13 - trans-prostenamide is prepared by hydrogenatin...

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Bibliographische Detailangaben
Hauptverfasser:	T K SCHAAF, H-J E HESS
Format:	Patent
Sprache:	swe
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	1456838 Silylated prostaglandins PFIZER Inc 8 Nov 1973 [8 Nov 1972] 51997/73 Heading C3S [Also in Division C2] N - Methansulphonyl - 15 - (5,6 - dimethoxy- 2 - indanyl) - 9α,11α,15# - tris - (dimethylisopropylsilyloxy) - 16,17,18,19,20 - pentanor - 13 - trans-prostenamide is prepared by hydrogenating N-methanesulphonyl-15-(5,6-dimethoxy-2- indanyl) - 9α,11α,15# - tris - (dimethylisopropylsilyloxy) - 16,17,18,19,20 - pentanor - 5 - cis, 13- trans-prostadienamide, resulting from the reaction between dimethylisopropylchlorosilane and N - methanesulphonyl - 9α,11α,15# - trihydroxy - 16,17,18,19,20 - pentanor - 5 - cis, 13- trans - prostadienamide. 16 - (2 - Indonyl)- 11α,15α - bis - (dimethylisopropylsilyloxy) - 9- oxo - 17,18,19,20 - tetranor - 13 - trans - prostenoic acid and 16-(2-indanyl)-11α,15α-bis-(dimethylisopropylsilyloxy) - 9 - oxo - 17,18.19,20- tetranor-5-cis, 13-trans-prostadienoic acid are obtained in a similar manner.