1-(HYDROXIMETYL)-1,6,7,11B-TETRAHYDRO-2H,4H-/1,3/-OXAZINO- ELLER -TIAZINO/4,3-A/ISOKINOLINDERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH FARMACEUTISKA KOMPOSITIONER INNEHAALLANDE DEM

The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), (I) wherein R1 and R2 are alkoxy having from 1 to 6 carbon atoms, X is oxygen or sulfur, Y is =O, =S or an =NR3 group, wherein R3 is hydrogen, alkyl ha...

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Hauptverfasser: 5)A KALMAN, 10)L SZPORNY, 1)G BERNATH, 6)E EZER, 3)F FULOEP, 8)E PALOSI, 4)A SOHAJDA, 9)L DENES, 2)J KOBOR, 7)G HAJOS
Format: Patent
Sprache:swe
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Zusammenfassung:The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), (I) wherein R1 and R2 are alkoxy having from 1 to 6 carbon atoms, X is oxygen or sulfur, Y is =O, =S or an =NR3 group, wherein R3 is hydrogen, alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms or optionally substituted phenyl, and acid addition and quaternary salts thereof.