2-(o-carboxyphenylamino)-6H-pyrimido(2,1-b)quinazoline and derivative thereof and compositions thereof
Pharmaceutically usable 2-(o-carboxyphenylamino)-6H-pyrimido(2,1-b)quinazoline 6 with the formulaFurther derivative of this compound with the formulawhere A+ is an alkaline metal, monoethanolamine or diethylamine.IN addition a derivative of the stated compound with the formulawhere R represents OH o...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
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Format: | Patent |
Sprache: | eng ; swe |
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Zusammenfassung: | Pharmaceutically usable 2-(o-carboxyphenylamino)-6H-pyrimido(2,1-b)quinazoline 6 with the formulaFurther derivative of this compound with the formulawhere A+ is an alkaline metal, monoethanolamine or diethylamine.IN addition a derivative of the stated compound with the formulawhere R represents OH or alkyloxide with 1-4 carbon atoms or NHR2, where R1 represents H, alkyl with 1-4 carbon atoms or phenyl as well as alkyl and A are salts of inorganic acids.The final derivative of the given compound with the formulawhere R represents alkyloxide with 1-4 carbon atoms or R1 represents alkyl with 1-4 carbon atoms.Furthermore, a process for producing the given formula comprising in that 2.4 dichloropyrimidine is converted with a sodium salt of anthranilic acid or subtitesters or amides of anthranilic acid in a hydrous or an organic solution at 90-120 degrees C for several hours.Furthermore, this refers to a hemotherapeutic composition, in which the component contains the above given compound or that and a pharmaceutically approved carrier material. |
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