SIBSTITUERAT CYKLOPENTANDERIVAT TILL ANVENDNING SOM MELLANPRODUKT VID FRAMSTELLNING AV FARMACEUTISKT AKTIVA PROSTAGLANDINANALOGER

In the synthesis of prostaglandins of the "one"-series an alteration in the conventional reaction sequence avoids side reactions and provides an improved synthesis via a series of novel intermediates. In this improved synthesis the side chain at the 8 position is attached to the five membe...

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Hauptverfasser: T K SCHAAF, E J COREY
Format: Patent
Sprache:swe
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Zusammenfassung:In the synthesis of prostaglandins of the "one"-series an alteration in the conventional reaction sequence avoids side reactions and provides an improved synthesis via a series of novel intermediates. In this improved synthesis the side chain at the 8 position is attached to the five membered ring before the side chain at the 12 position is attached.