FORFARANDE ATT GENOM ACYLERING VID 100-220Ÿ C I INERTA LOSNINGSMEDEL FRAMSTELLA DERIVAT AV 1-BENSOYL-2-METYL-5-METOXI-3-INDOLYLETTIKSYROR

FORFARANDE ATT GENOM ACYLERING VID 100-220Ÿ C I INERTA LOSNINGSMEDEL FRAMSTELLA DERIVAT AV 1-BENSOYL-2-METYL-5-METOXI-3-INDOLYLETTIKSYROR

1417080 Process for benzoylating indoles TROPON GmbH [trading as TROPONWERKE DINKLAGE & CO] 23 Nov 1973 [25 Nov 1972] 54400/73 Heading C2C A process for making compounds of formula wherein R is PhCH 2 - or PhCH 2 O 2 CCH 2 - and X is H, or one or more halogen atoms or functional groups, comprise...

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Bibliographische Detailangaben
Hauptverfasser: P-R SEIDEL, O BRENDLER, K-H BOLTZE
Format: Patent
Sprache:swe
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:1417080 Process for benzoylating indoles TROPON GmbH [trading as TROPONWERKE DINKLAGE & CO] 23 Nov 1973 [25 Nov 1972] 54400/73 Heading C2C A process for making compounds of formula wherein R is PhCH 2 - or PhCH 2 O 2 CCH 2 - and X is H, or one or more halogen atoms or functional groups, comprises reacting together in an inert solvent at #100‹ C., the corresponding N-unsubstituted indole and benzoyl chloride, with formation of free HCl. The products may be hydrogenolysed to the corresponding acids, i.e. analogues having otherwise the above structure but containing -CH 2 CO 2 H or -CH 2 CO 2 CH 2 CO 2 H in the 3-position of the indole nucleus.