SE378422

1,245,316. Quinazolinone derivative. TROPON G.m.b.H., [trading as TROPONWERKE DINKLAGE & CO.]. 7 Oct., 1969 [16 Oct., 1968], No. 49142/69. Heading C2C. Novel 2 - methyl - 3 - {3 - (4 - phenylpiperazin - 1 - yl) - 2 - hydroxy - propyl}- quinazolin-4-one is prepared by reaction of 1- phenyl-pipera...

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Bibliographische Detailangaben
Hauptverfasser:	BOLTZE K-H, LORENZ D
Format:	Patent
Sprache:	eng
Schlagworte:	BASIC ELECTRIC ELEMENTS CHEMISTRY ELECTRICITY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INDUCTANCES MAGNETS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES TRANSFORMERS
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Zusammenfassung:	1,245,316. Quinazolinone derivative. TROPON G.m.b.H., [trading as TROPONWERKE DINKLAGE & CO.]. 7 Oct., 1969 [16 Oct., 1968], No. 49142/69. Heading C2C. Novel 2 - methyl - 3 - {3 - (4 - phenylpiperazin - 1 - yl) - 2 - hydroxy - propyl}- quinazolin-4-one is prepared by reaction of 1- phenyl-piperazine with 2-methyl-3-(3-bromo-2- hydroxypropyl) - quinazolin - 4 - one or 2- methyl - 3 - (2,3 - epoxypropyl) - quinazoline-4- one, which latter compound may be prepared in situ by reaction of 2-methyl-quinazoline-4-one with epichlorohydrin. Pharmaceutical compositions comprise the novel compound together with a suitable carrier and are administered orally as analgesics and antitussives.