N-(3-AMINOPROPYL)-N-PHENYL-5,6,7,8-TETRAHYDRONAPHTHALENE- 2-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF IN THERAPY

FIELD: medicine. SUBSTANCE: claimed invention describes compounds of general formula (I):wherein Ris hydrogen or halogen atom, either methyl or C-Calkoxy group; hydrogen or halogen atom;is hydrogen atom or methoxy group; C-Cis alkyl group; Ris 2,3- dihydroxy-1H-inden-2-yl, 2,3-dihydro-1H-inden-1-yl,...

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Bibliographische Detailangaben
Hauptverfasser:	FROST DZHONATAN, BARCH REZHIN, ZHORZH PASKAL, VIL'JAMS POL KHAUARD, RUSSEL' KORINN, PASO PATRIK, MJULLER ZHAN-KLOD
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine. SUBSTANCE: claimed invention describes compounds of general formula (I):wherein Ris hydrogen or halogen atom, either methyl or C-Calkoxy group; hydrogen or halogen atom;is hydrogen atom or methoxy group; C-Cis alkyl group; Ris 2,3- dihydroxy-1H-inden-2-yl, 2,3-dihydro-1H-inden-1-yl, or 1,2,3,4-tetrahydronaphthalen-1-yl group, or alternatively Rand Rtogether with nitrogen atom form 1,2,3,4- tetrahydroisoquinolin-2-yl, 6,7-dimethoxy, 1,2,3,4- tetrahydroisoquinolin-2-yl, 5,8-dimethoxy-1,2,3,4- tetrahydroisoquinolin-2-yl, 1,2,3,4-tetrahydro-9H-pyrido (3,4-b) indol-2-yl, 1,2,3,4-tetrahydro-9H-pyrido (4,3-b) indol-3-yl, 4,5,6,7-tetrahydrothieno (2,3-c) pyrid-6-yl, 2,3-dihydro-1H-isoindol-2-yl or 2,3,4,5-tetrahydro-1H-3- benzazepin-3-yl group. EFFECT: improved properties of the title compounds. Соединения, отвечающие общей формуле, приведенной в описании.