CYCLOHEXANE DERIVATIVES, PHARMCOMPOSITION BASED THEREON, AND METHOD OF TREATMENT

FIELD: medicine. SUBSTANCE: claimed invention describes preparation of novel cyclohexane derivative represented by formula (I) or pharmacologically acceptable salt thereof:wherein each of Rand Ris identical or different and is hydrogen atom or lower alkyl; Ris optionally substituted aryl or optional...

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Bibliographische Detailangaben
Hauptverfasser:	KEJDZI ISIBASI, KATSUKHIRO MORIJA, KHITOSI OJNUMA, MANABU SIRATO, SATOSI KATAJAMA, TOSIAKI OGAVA, SIGERU SOUDA, FUMIKHIRO OZAKI, TAKASI KHASEGAVA, JASUKHIRO KABASAVA
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine. SUBSTANCE: claimed invention describes preparation of novel cyclohexane derivative represented by formula (I) or pharmacologically acceptable salt thereof:wherein each of Rand Ris identical or different and is hydrogen atom or lower alkyl; Ris optionally substituted aryl or optionally substituted heteroaryl; X is oxygen or sulfur atom and Y is group of formula:or the like. Compound of the claimed invention may be used as prophylactic or therapeutic agent for treatment of diseases which has potassium passage opening effect. EFFECT: improved properties of the novel as cyclohexane derivative. Соединение может быть использовано в качестве профилактического или терапевтического средства для лечения заболеваний, против которых эффективно открывающее калиевые каналы действие.