BIFUNCTIONAL VARIANTS OF UROKINASE WITH IMPROVED FIBRINOLYTIC PROPERTIES AND ACTION INHIBITING THROMBIN
FIELD: biochemistry, enzymology. SUBSTANCE: invention describes the bifunctional variants of urokinase with the improved fibrinolytic properties and capability to inhibit thrombin activity, plasmids used for these polypeptides preparing and thrombolytics containing bifunctional variant of urokinase...
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| creator | DEREK DZHON SONDERS GERD J.SHTEFFENS STEFAN VNENDT JOKHANNES SHNAJDER REGINA KHAJNTSEL'-VILAND |
| description | FIELD: biochemistry, enzymology. SUBSTANCE: invention describes the bifunctional variants of urokinase with the improved fibrinolytic properties and capability to inhibit thrombin activity, plasmids used for these polypeptides preparing and thrombolytics containing bifunctional variant of urokinase as biologically active substance. EFFECT: improved properties of preparation.
Предложены бифункциональные варианты урокиназы с улучшенными фибринолитическими свойствами и ингибирующим тромбин действием, применяемые при получении этих полипептидов плазмиды, а также тромболитические средства, которые в качестве биологически активного вещества содержат бифункциональный варинт урокиназы. |
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Предложены бифункциональные варианты урокиназы с улучшенными фибринолитическими свойствами и ингибирующим тромбин действием, применяемые при получении этих полипептидов плазмиды, а также тромболитические средства, которые в качестве биологически активного вещества содержат бифункциональный варинт урокиназы.</description><language>eng ; rus</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970310&DB=EPODOC&CC=RU&NR=94026095A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970310&DB=EPODOC&CC=RU&NR=94026095A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DEREK DZHON SONDERS</creatorcontrib><creatorcontrib>GERD J.SHTEFFENS</creatorcontrib><creatorcontrib>STEFAN VNENDT</creatorcontrib><creatorcontrib>JOKHANNES SHNAJDER</creatorcontrib><creatorcontrib>REGINA KHAJNTSEL'-VILAND</creatorcontrib><title>BIFUNCTIONAL VARIANTS OF UROKINASE WITH IMPROVED FIBRINOLYTIC PROPERTIES AND ACTION INHIBITING THROMBIN</title><description>FIELD: biochemistry, enzymology. SUBSTANCE: invention describes the bifunctional variants of urokinase with the improved fibrinolytic properties and capability to inhibit thrombin activity, plasmids used for these polypeptides preparing and thrombolytics containing bifunctional variant of urokinase as biologically active substance. EFFECT: improved properties of preparation.
Предложены бифункциональные варианты урокиназы с улучшенными фибринолитическими свойствами и ингибирующим тромбин действием, применяемые при получении этих полипептидов плазмиды, а также тромболитические средства, которые в качестве биологически активного вещества содержат бифункциональный варинт урокиназы.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1997</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjE0KwjAUBrtxIeod3gWE4h-4TNrEfNi-lPS14qoUiW5EC_X-KOIBXA0Mw0yTm4ZtOBN4VgW1KkCx1OQtNcEfwao2dII4QlkF35qcLHQA--IsyOjjKhMEpibFOanviMAOGgI-kLjgSw2eJ5Nrfx_j4sdZQtZI5pZxeHZxHPpLfMRXF5r9Jl3t0v1Wrf9I3uHoNcA</recordid><startdate>19970310</startdate><enddate>19970310</enddate><creator>DEREK DZHON SONDERS</creator><creator>GERD J.SHTEFFENS</creator><creator>STEFAN VNENDT</creator><creator>JOKHANNES SHNAJDER</creator><creator>REGINA KHAJNTSEL'-VILAND</creator><scope>EVB</scope></search><sort><creationdate>19970310</creationdate><title>BIFUNCTIONAL VARIANTS OF UROKINASE WITH IMPROVED FIBRINOLYTIC PROPERTIES AND ACTION INHIBITING THROMBIN</title><author>DEREK DZHON SONDERS ; GERD J.SHTEFFENS ; STEFAN VNENDT ; JOKHANNES SHNAJDER ; REGINA KHAJNTSEL'-VILAND</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU94026095A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>1997</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DEREK DZHON SONDERS</creatorcontrib><creatorcontrib>GERD J.SHTEFFENS</creatorcontrib><creatorcontrib>STEFAN VNENDT</creatorcontrib><creatorcontrib>JOKHANNES SHNAJDER</creatorcontrib><creatorcontrib>REGINA KHAJNTSEL'-VILAND</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DEREK DZHON SONDERS</au><au>GERD J.SHTEFFENS</au><au>STEFAN VNENDT</au><au>JOKHANNES SHNAJDER</au><au>REGINA KHAJNTSEL'-VILAND</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BIFUNCTIONAL VARIANTS OF UROKINASE WITH IMPROVED FIBRINOLYTIC PROPERTIES AND ACTION INHIBITING THROMBIN</title><date>1997-03-10</date><risdate>1997</risdate><abstract>FIELD: biochemistry, enzymology. SUBSTANCE: invention describes the bifunctional variants of urokinase with the improved fibrinolytic properties and capability to inhibit thrombin activity, plasmids used for these polypeptides preparing and thrombolytics containing bifunctional variant of urokinase as biologically active substance. EFFECT: improved properties of preparation.
Предложены бифункциональные варианты урокиназы с улучшенными фибринолитическими свойствами и ингибирующим тромбин действием, применяемые при получении этих полипептидов плазмиды, а также тромболитические средства, которые в качестве биологически активного вещества содержат бифункциональный варинт урокиназы.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | BIFUNCTIONAL VARIANTS OF UROKINASE WITH IMPROVED FIBRINOLYTIC PROPERTIES AND ACTION INHIBITING THROMBIN |
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