DERIVATIVES OF 2-AMINO-4-HETEROARYL-1,4-DIHYDROPYRIDINE, MIXTURE OF THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS

DERIVATIVES OF 2-AMINO-4-HETEROARYL-1,4-DIHYDROPYRIDINE, MIXTURE OF THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS

FIELD: organic chemistry. SUBSTANCE: product: derivatives of 2-amino-4-heteroaryl-1,4-dihydropyridine of the general formulawhere: values R-Rwere given in the claim description, mixtures of their isomers or individual isomers and their salts that show valuable spectrum of pharmacological activity an...

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Hauptverfasser: JOAKHIM KHJUTTER, ALEKSANDER SHTRAUB, JURGEN SHTOL'TEFUS, RAJNER GROS, MARTIN BEKHEM, ZIGBERT KHEBISH, ZIGFRID GOL'DMANN, KHAUEHD-POL RAUNDING
Format: Patent
Sprache:eng ; rus
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:FIELD: organic chemistry. SUBSTANCE: product: derivatives of 2-amino-4-heteroaryl-1,4-dihydropyridine of the general formulawhere: values R-Rwere given in the claim description, mixtures of their isomers or individual isomers and their salts that show valuable spectrum of pharmacological activity and effect, in part, on heart contraction and smooth muscle tone. EFFECT: improved method of synthesis, enhanced curative effectiveness. Объектом изобретения являются производные 2-амино-4-гетероарил-1,4-дигидропиридина общей формулы I, приведенной в описании. смеси их изомеров или отдельные изомеры и их соли, которые обладают ценным спектром фармакологической активности и, в частности, влияют на способность сокращения сердца и тонус гладкой мускулатуры.