METHOD OF INCREASING EFFICIENCY OF COMBINED THERAPY IN LOCAL RADIATION DAMAGE

FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, namely to treatment of patients with local radiation damage. The method includes taking fatty tissue from the patient in the lower third of the anterior abdominal wall by syringe liposuction. A stromal vascular fraction...

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Bibliographische Detailangaben
Hauptverfasser:	Udalov Yurij Dmitrievich, Usupzhanova Darya Yurevna, Brunchukov Vitalij Andreevich, Samojlov Aleksandr Sergeevich, Kobzeva Irina Vladimirovna, Astrelina Tatyana Alekseevna, Suchkova Yuliya Borisovna, Aksenenko Arkadij Vladimirovich
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, namely to treatment of patients with local radiation damage. The method includes taking fatty tissue from the patient in the lower third of the anterior abdominal wall by syringe liposuction. A stromal vascular fraction of fatty tissue is extracted from the obtained lipoapirate by enzymatic treatment, washing and filtration, wherein the fraction consists of stromal cells (15 to 30%, wherein: 3% are stem cells and precursor cells - positive expression of CD105, CD90, CD73), endothelial cells (10 to 20% - positive expression of more than CD31), blood cells (5 to 15% - positive expression of CD45), pericytes (3 to 5% - positive expression of CD146), hemopoietic stem cells (