AMATHOXINE-ANTIBODY CONJUGATES

FIELD: pharmaceuticals.SUBSTANCE: invention relates to a conjugate of general formula: Ama-L-X-S-Ab, in which Ama is an amatoxin, L is a linker, X is a fragment obtained by binding a thiol group with a thiol-reacting group, S is a sulfur atom of an amino acid residue of cysteine and Ab is an antibod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MYULLER Kristof, KHEKHLER Torsten, PAL Andreas, ANDERL Yan
Format: Patent
Sprache:eng ; rus
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