SUBSTITUTED 2H-PYRAZOLE DERIVATIVE

SUBSTITUTED 2H-PYRAZOLE DERIVATIVE

FIELD: pharmaceutics.SUBSTANCE: invention relates to novel substituted 2H-pyrazole derivative acting as a selective inhibitor of CDK4/6. In particular, the disclosed invention is a substance of formula (I) or a pharmaceutically acceptable salt thereof, which acts as a selective inhibitor of CDK4/6.E...

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Bibliographische Detailangaben
Hauptverfasser: SYU, Chzhaobin, DIN, Charlz Z, CHZHAO, Baopin, LYU, Inchun, VAN, Fej, LIN, Rujbin, CHEN, Shukhuej, LI, Tszyan
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:FIELD: pharmaceutics.SUBSTANCE: invention relates to novel substituted 2H-pyrazole derivative acting as a selective inhibitor of CDK4/6. In particular, the disclosed invention is a substance of formula (I) or a pharmaceutically acceptable salt thereof, which acts as a selective inhibitor of CDK4/6.EFFECT: disclosed is substituted 2H-pyrazole derivative.18 cl, 4 tbl, 35 ex Изобретение относится к новому замещенному производному 2Н-пиразолу, выступающему в роли селективного ингибитора CDK4/6. В частности, раскрытое изобретение представляет собой вещество с формулой (I) или его фармацевтически приемлемую соль, которая выступает в качестве селективного ингибитора CDK4/6.2 н. и 16 з.п. ф-лы, 4 табл., 35 пр.