BETA-SECRETASE INHIBITORS

FIELD: medicine; pharmaceuticals.SUBSTANCE: invention refers to compounds of formula I, as well as to pharmaceutical compositions based thereon.EFFECT: technical result is obtaining novel compounds having BACE1 inhibitor activity, useful in therapeutic and/or preventive treatment of mediated disease...

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Bibliographische Detailangaben
Hauptverfasser:	KHAAP Volfgang, PETERS Jens-Uve, BARTELS Bern, OBST ZANDER Ulrike, GUBA Volfgang, VOLTERING Tomas, DOLENTE Kozimo
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine; pharmaceuticals.SUBSTANCE: invention refers to compounds of formula I, as well as to pharmaceutical compositions based thereon.EFFECT: technical result is obtaining novel compounds having BACE1 inhibitor activity, useful in therapeutic and/or preventive treatment of mediated diseases.22 cl, 9 tbl, 44 ex Изобретение относится к соединениям формулы I, а также к фармацевтическим композициям на их основе. Технический результат: получены новые соединения, обладающее активностью ингибитора ВАСЕ1, полезные в терапевтическом и/или профилактическом лечении опосредованных заболеваний. 4 н. и 18 з.п. ф-лы, 9 табл., 44 прим.