IMIDAZOPYRROLOPYRINE DERIVATIVES USEFUL FOR TREATING DISEASES CAUSED BY ABNORMAL ACTIVITY OF PROTEIN KINASES JAK1, JAK3 OR SYK

IMIDAZOPYRROLOPYRINE DERIVATIVES USEFUL FOR TREATING DISEASES CAUSED BY ABNORMAL ACTIVITY OF PROTEIN KINASES JAK1, JAK3 OR SYK

FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and specifically to a compound of the structure given below and a pharmaceutically acceptable salt thereof.EFFECT: technical result is obtaining a novel heterocyclic compound useful for treating various pathological conditions mediat...

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Hauptverfasser: STYUART Kent D, ERIKSSON Anna M, MORYTKO Majkl Dzh, VOSS Dzheffri V, ARDZHIRIADI Mariya A, DZHORZH Don M, FRENK Kristin E, VISHART Nil, GODKEN Erik R, LI Bitsin S, KOLDERVUD Devid Dzh, VAN Lu, FYAMENGO Brajan A, UOLLEJS Grir A, FRIDMAN Majkl, VOLLER Kevin R, DZHOZEFSON Natan S
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and specifically to a compound of the structure given below and a pharmaceutically acceptable salt thereof.EFFECT: technical result is obtaining a novel heterocyclic compound useful for treating various pathological conditions mediated by abnormal activity of kinases of JAK family, and in particular for treating rheumatoid arthritis.1 cl, 54 tbl, 690 ex Изобретение относится к области органической химии, а именно к соединению указанной ниже структуры и к его фармацевтически приемлемой соли. Технический результат: получено новое гетероциклическое соединение, полезное для лечения различных патологических состояний, опосредованных аномальной активностью киназ семейства JAK, и, в частности, для лечения ревматоидного артрита. 1 з.п. ф-лы, 54 табл., 690 пр.