METHOD FOR SURGICAL TREATMENT OF STRICTURES OF THE ANTERIOR URETHRA IN MALES

FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly to urology. Method involves urethrotomy and the introduction of a suspension in the urethra consisting of milled buccal mucosa and fibrin-thrombin glue. First, area of buccal mucosa Sb taken as constituent 1/3 of wound surface area in urethra after urethrotomy Su, area Su is calculated by formula: Su=πl(1-d), where l is length of stricture in cm, determined X-ray, +1 cm, d - initial minimum diameter of urethra in area of stricture, determined X-ray. Produced flap of buccal mucosa is washed in a solution of antibiotics with volume of 2 ml. Flap is fragmented to particles sized to 1 mm; the graft fragments in the antibiotic solution are subjected to centrifugation in mode of 1,700 rpm for 5 minutes. Obtained sediment is resuspended in 1 ml of said antibiotic solution and divided into 2 parts, each of which is mixed with one of two components of fibrin-thrombin glue, equal in volume, wherein total amount of adhesive is calculated by formula: V=0.18πl, where l is a stricture length in cm, determined X-ray, +1 cm, performing an internal optical urethrotomy, method involves installing urethral 16 Ch diameter catheter parallel to which a two-pass ureteral catheter is delivered to the incision site, whereby two components of the glue with suspension of buccal mucosa fragments are introduced simultaneously with the syringe; the urethral catheter is removed 14-21 days after the operation.EFFECT: method enables providing higher effectiveness and reducing intraoperative injuries by minimally invasive intervention and forming an integral, seamless suture of neo-urethra in postoperative recovery.1 cl, 2 dwg, 1 ex Изобретение относится к медицине, в частности к урологии. Способ включает проведение уретротомии и введение в уретру суспензии, состоящей из измельченной буккальной слизистой и фибрин-тромбинового клея. Сначала определяют площадь забираемого лоскута буккальной слизистой Sb как составляющую 1/3 часть площади раневой поверхности в уретре после уретротомии Su, при этом площадь Su рассчитывают по формуле: Su=πl(1-d), где l - длина стриктуры в см, определенная рентгенологически, +1 см, d - исходный минимальный диаметр уретры в зоне стриктуры, определенный рентгенологически. Полученный лоскут буккальной слизистой промывают в растворе антибиотиков объемом от 2 мл. Производят фрагментацию лоскута до частиц размерами порядка 1 мм, взвесь фрагментов трансплантата в растворе антибиотиков подвергают цент