THIAZOLOPYRIMIDINONES AS MODULATORS OF NMDA RECEPTOR ACTIVITY

FIELD: chemistry.SUBSTANCE: invention relates to thiazolopyrimidinone compounds of formula (II) and pharmaceutical compositions based thereon.EFFECT: technical result is obtaining novel compounds which can be used as a drug exhibiting activity of NR2A-selective modulation of NMDA receptor.67 cl, 3 t...

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Hauptverfasser:	VOLGRAF Metyu, SELLERS Bendzhamin, YUJ Tszyan, VILLEMUR Eliziya, LI Kuon, SHVARTS Yakob, U Goshen, YUEN Po-Vaj
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: chemistry.SUBSTANCE: invention relates to thiazolopyrimidinone compounds of formula (II) and pharmaceutical compositions based thereon.EFFECT: technical result is obtaining novel compounds which can be used as a drug exhibiting activity of NR2A-selective modulation of NMDA receptor.67 cl, 3 tbl, 267 ex Изобретение относится к тиазолопиримидиноновым соединениям формулы (II) и фармацевтическим композициям на их основе. Технический результат: получены новые соединения, которые могут быть применимы в качестве лекарственного средства, обладающего активностью NR2A-селективного модулирования рецептора NMDA. 3 н. и 64 з.п. ф-лы, 3 табл., 267 пр.