NEW DERIVATIVE OF 3-AZABICYCLO[3.1.0]HEXANE AND USE THEREOF FOR MEDICAL PURPOSES
FIELD: chemistry.SUBSTANCE: objective of the present invention is to obtain a compound of formula (I), having p-opioid receptor antagonist action, which causes less side effects, hence, is less safe, or a pharmacologically acceptable salt thereof, and preparing a medicinal agent for use in preventin...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | TSUDZAKI Yasunori IMURA Yuuki AKADZA Khiroto OKABE Morio KIMURA Tomio MIYADZAVA Tosiyuki IDZUTI Toru SETOGUTI Khiroyuki IVAMURA Rio KHARADA Satoko SIMIDZU Motokhisa KURUMADZUKA Dajsuke TANIKO Kaori KANEKO Tatsurokh |
| description | FIELD: chemistry.SUBSTANCE: objective of the present invention is to obtain a compound of formula (I), having p-opioid receptor antagonist action, which causes less side effects, hence, is less safe, or a pharmacologically acceptable salt thereof, and preparing a medicinal agent for use in preventing or treating itch based on antagonistic action on μ-opioid receptors.EFFECT: disclosed is new 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes.15 cl, 7 tbl, 42 ex
Задачей настоящего изобретения является получение соединения формулы (I), обладающего антагонистическим действием в отношении µ-опиоидных рецепторов, которое вызывает меньшие побочные эффекты, следовательно, является менее безопасным, или его фармакологически приемлемой соли, и получение лекарственного средства для применения в профилактике или лечении зуда, основанного на антагонистическом действии в отношении µ-опиоидных рецепторов. 2 н. и 13 з.п. ф-лы, 7 табл., 42 пр. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2701861C1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2701861C1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2701861C13</originalsourceid><addsrcrecordid>eNrjZAjwcw1XcHEN8gxzDPEMc1Xwd1Mw1nWMcnTydI509vGPNtYz1DOI9XCNcPRzVXD0c1EIDXZVCPFwDXIFqnTzD1LwdXXxdHb0UQgIDQrwD3YN5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8UGhRuYGhhZmhs6GxkQoAQDZxy5R</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NEW DERIVATIVE OF 3-AZABICYCLO[3.1.0]HEXANE AND USE THEREOF FOR MEDICAL PURPOSES</title><source>esp@cenet</source><creator>TSUDZAKI Yasunori ; IMURA Yuuki ; AKADZA Khiroto ; OKABE Morio ; KIMURA Tomio ; MIYADZAVA Tosiyuki ; IDZUTI Toru ; SETOGUTI Khiroyuki ; IVAMURA Rio ; KHARADA Satoko ; SIMIDZU Motokhisa ; KURUMADZUKA Dajsuke ; TANIKO Kaori ; KANEKO Tatsurokh</creator><creatorcontrib>TSUDZAKI Yasunori ; IMURA Yuuki ; AKADZA Khiroto ; OKABE Morio ; KIMURA Tomio ; MIYADZAVA Tosiyuki ; IDZUTI Toru ; SETOGUTI Khiroyuki ; IVAMURA Rio ; KHARADA Satoko ; SIMIDZU Motokhisa ; KURUMADZUKA Dajsuke ; TANIKO Kaori ; KANEKO Tatsurokh</creatorcontrib><description>FIELD: chemistry.SUBSTANCE: objective of the present invention is to obtain a compound of formula (I), having p-opioid receptor antagonist action, which causes less side effects, hence, is less safe, or a pharmacologically acceptable salt thereof, and preparing a medicinal agent for use in preventing or treating itch based on antagonistic action on μ-opioid receptors.EFFECT: disclosed is new 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes.15 cl, 7 tbl, 42 ex
Задачей настоящего изобретения является получение соединения формулы (I), обладающего антагонистическим действием в отношении µ-опиоидных рецепторов, которое вызывает меньшие побочные эффекты, следовательно, является менее безопасным, или его фармакологически приемлемой соли, и получение лекарственного средства для применения в профилактике или лечении зуда, основанного на антагонистическом действии в отношении µ-опиоидных рецепторов. 2 н. и 13 з.п. ф-лы, 7 табл., 42 пр.</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191002&DB=EPODOC&CC=RU&NR=2701861C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191002&DB=EPODOC&CC=RU&NR=2701861C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TSUDZAKI Yasunori</creatorcontrib><creatorcontrib>IMURA Yuuki</creatorcontrib><creatorcontrib>AKADZA Khiroto</creatorcontrib><creatorcontrib>OKABE Morio</creatorcontrib><creatorcontrib>KIMURA Tomio</creatorcontrib><creatorcontrib>MIYADZAVA Tosiyuki</creatorcontrib><creatorcontrib>IDZUTI Toru</creatorcontrib><creatorcontrib>SETOGUTI Khiroyuki</creatorcontrib><creatorcontrib>IVAMURA Rio</creatorcontrib><creatorcontrib>KHARADA Satoko</creatorcontrib><creatorcontrib>SIMIDZU Motokhisa</creatorcontrib><creatorcontrib>KURUMADZUKA Dajsuke</creatorcontrib><creatorcontrib>TANIKO Kaori</creatorcontrib><creatorcontrib>KANEKO Tatsurokh</creatorcontrib><title>NEW DERIVATIVE OF 3-AZABICYCLO[3.1.0]HEXANE AND USE THEREOF FOR MEDICAL PURPOSES</title><description>FIELD: chemistry.SUBSTANCE: objective of the present invention is to obtain a compound of formula (I), having p-opioid receptor antagonist action, which causes less side effects, hence, is less safe, or a pharmacologically acceptable salt thereof, and preparing a medicinal agent for use in preventing or treating itch based on antagonistic action on μ-opioid receptors.EFFECT: disclosed is new 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes.15 cl, 7 tbl, 42 ex
Задачей настоящего изобретения является получение соединения формулы (I), обладающего антагонистическим действием в отношении µ-опиоидных рецепторов, которое вызывает меньшие побочные эффекты, следовательно, является менее безопасным, или его фармакологически приемлемой соли, и получение лекарственного средства для применения в профилактике или лечении зуда, основанного на антагонистическом действии в отношении µ-опиоидных рецепторов. 2 н. и 13 з.п. ф-лы, 7 табл., 42 пр.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAjwcw1XcHEN8gxzDPEMc1Xwd1Mw1nWMcnTydI509vGPNtYz1DOI9XCNcPRzVXD0c1EIDXZVCPFwDXIFqnTzD1LwdXXxdHb0UQgIDQrwD3YN5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8UGhRuYGhhZmhs6GxkQoAQDZxy5R</recordid><startdate>20191002</startdate><enddate>20191002</enddate><creator>TSUDZAKI Yasunori</creator><creator>IMURA Yuuki</creator><creator>AKADZA Khiroto</creator><creator>OKABE Morio</creator><creator>KIMURA Tomio</creator><creator>MIYADZAVA Tosiyuki</creator><creator>IDZUTI Toru</creator><creator>SETOGUTI Khiroyuki</creator><creator>IVAMURA Rio</creator><creator>KHARADA Satoko</creator><creator>SIMIDZU Motokhisa</creator><creator>KURUMADZUKA Dajsuke</creator><creator>TANIKO Kaori</creator><creator>KANEKO Tatsurokh</creator><scope>EVB</scope></search><sort><creationdate>20191002</creationdate><title>NEW DERIVATIVE OF 3-AZABICYCLO[3.1.0]HEXANE AND USE THEREOF FOR MEDICAL PURPOSES</title><author>TSUDZAKI Yasunori ; IMURA Yuuki ; AKADZA Khiroto ; OKABE Morio ; KIMURA Tomio ; MIYADZAVA Tosiyuki ; IDZUTI Toru ; SETOGUTI Khiroyuki ; IVAMURA Rio ; KHARADA Satoko ; SIMIDZU Motokhisa ; KURUMADZUKA Dajsuke ; TANIKO Kaori ; KANEKO Tatsurokh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2701861C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TSUDZAKI Yasunori</creatorcontrib><creatorcontrib>IMURA Yuuki</creatorcontrib><creatorcontrib>AKADZA Khiroto</creatorcontrib><creatorcontrib>OKABE Morio</creatorcontrib><creatorcontrib>KIMURA Tomio</creatorcontrib><creatorcontrib>MIYADZAVA Tosiyuki</creatorcontrib><creatorcontrib>IDZUTI Toru</creatorcontrib><creatorcontrib>SETOGUTI Khiroyuki</creatorcontrib><creatorcontrib>IVAMURA Rio</creatorcontrib><creatorcontrib>KHARADA Satoko</creatorcontrib><creatorcontrib>SIMIDZU Motokhisa</creatorcontrib><creatorcontrib>KURUMADZUKA Dajsuke</creatorcontrib><creatorcontrib>TANIKO Kaori</creatorcontrib><creatorcontrib>KANEKO Tatsurokh</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TSUDZAKI Yasunori</au><au>IMURA Yuuki</au><au>AKADZA Khiroto</au><au>OKABE Morio</au><au>KIMURA Tomio</au><au>MIYADZAVA Tosiyuki</au><au>IDZUTI Toru</au><au>SETOGUTI Khiroyuki</au><au>IVAMURA Rio</au><au>KHARADA Satoko</au><au>SIMIDZU Motokhisa</au><au>KURUMADZUKA Dajsuke</au><au>TANIKO Kaori</au><au>KANEKO Tatsurokh</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NEW DERIVATIVE OF 3-AZABICYCLO[3.1.0]HEXANE AND USE THEREOF FOR MEDICAL PURPOSES</title><date>2019-10-02</date><risdate>2019</risdate><abstract>FIELD: chemistry.SUBSTANCE: objective of the present invention is to obtain a compound of formula (I), having p-opioid receptor antagonist action, which causes less side effects, hence, is less safe, or a pharmacologically acceptable salt thereof, and preparing a medicinal agent for use in preventing or treating itch based on antagonistic action on μ-opioid receptors.EFFECT: disclosed is new 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes.15 cl, 7 tbl, 42 ex
Задачей настоящего изобретения является получение соединения формулы (I), обладающего антагонистическим действием в отношении µ-опиоидных рецепторов, которое вызывает меньшие побочные эффекты, следовательно, является менее безопасным, или его фармакологически приемлемой соли, и получение лекарственного средства для применения в профилактике или лечении зуда, основанного на антагонистическом действии в отношении µ-опиоидных рецепторов. 2 н. и 13 з.п. ф-лы, 7 табл., 42 пр.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2701861C1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NEW DERIVATIVE OF 3-AZABICYCLO[3.1.0]HEXANE AND USE THEREOF FOR MEDICAL PURPOSES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T15%3A50%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TSUDZAKI%20Yasunori&rft.date=2019-10-02&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2701861C1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |