SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS
FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and notably to specific imidazo[4,5-c]pyridine derivatives. Invention also relates to a pharmaceutical composition based on a specific imidazo[4,5-c]pyridine derivative useful in treating cancer.EFFECT: technical result is obtaining...
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| creator | SAMALA Dzhajya Prakash KAMMARANO Karolin Mishel ROJTERSHAN Majkl Khejl DOLL Ronald Dzh PANDA Dzhagannatkh YAN Lipin BODZHEN Stefan L TROTTER B. Uesli GKHOSH Partkha BOLISETTI Ragkhu VOSS Mettyu E FRADERA LINAS Fransesk Ksaver ALTMAN Majkl D TOMPSON Kristofer Frensis MARTINES Mishel MASHASEK Mishell KRISTOFER Mettyu P SUN Binyuan SIDZUKA Manami TONI KURISSERI Antkhappan |
| description | FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and notably to specific imidazo[4,5-c]pyridine derivatives. Invention also relates to a pharmaceutical composition based on a specific imidazo[4,5-c]pyridine derivative useful in treating cancer.EFFECT: technical result is obtaining novel imidazopyridine derivatives useful as HDM2 protein inhibitors.17 cl, 1 dwg, 21 tbl, 360 ex
Изобретение относится к области органической химии, а именно к конкретным производным имидазо[4,5-c]пиридина. Также изобретение относится к фармацевтической композиции на основе конкретного производного имидазо[4,5-c]пиридина, полезной для лечения рака. Технический результат: получены новые производные имидазопиридина, полезные в качестве ингибиторов HDM2 белка. 6 н. и 11 з.п. ф-лы, 1 ил., 21 табл., 360 пр. |
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Изобретение относится к области органической химии, а именно к конкретным производным имидазо[4,5-c]пиридина. Также изобретение относится к фармацевтической композиции на основе конкретного производного имидазо[4,5-c]пиридина, полезной для лечения рака. Технический результат: получены новые производные имидазопиридина, полезные в качестве ингибиторов HDM2 белка. 6 н. и 11 з.п. ф-лы, 1 ил., 21 табл., 360 пр.</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190605&DB=EPODOC&CC=RU&NR=2690663C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190605&DB=EPODOC&CC=RU&NR=2690663C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SAMALA Dzhajya Prakash</creatorcontrib><creatorcontrib>KAMMARANO Karolin Mishel</creatorcontrib><creatorcontrib>ROJTERSHAN Majkl Khejl</creatorcontrib><creatorcontrib>DOLL Ronald Dzh</creatorcontrib><creatorcontrib>PANDA Dzhagannatkh</creatorcontrib><creatorcontrib>YAN Lipin</creatorcontrib><creatorcontrib>BODZHEN Stefan L</creatorcontrib><creatorcontrib>TROTTER B. Uesli</creatorcontrib><creatorcontrib>GKHOSH Partkha</creatorcontrib><creatorcontrib>BOLISETTI Ragkhu</creatorcontrib><creatorcontrib>VOSS Mettyu E</creatorcontrib><creatorcontrib>FRADERA LINAS Fransesk Ksaver</creatorcontrib><creatorcontrib>ALTMAN Majkl D</creatorcontrib><creatorcontrib>TOMPSON Kristofer Frensis</creatorcontrib><creatorcontrib>MARTINES Mishel</creatorcontrib><creatorcontrib>MASHASEK Mishell</creatorcontrib><creatorcontrib>KRISTOFER Mettyu P</creatorcontrib><creatorcontrib>SUN Binyuan</creatorcontrib><creatorcontrib>SIDZUKA Manami</creatorcontrib><creatorcontrib>TONI KURISSERI Antkhappan</creatorcontrib><title>SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS</title><description>FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and notably to specific imidazo[4,5-c]pyridine derivatives. Invention also relates to a pharmaceutical composition based on a specific imidazo[4,5-c]pyridine derivative useful in treating cancer.EFFECT: technical result is obtaining novel imidazopyridine derivatives useful as HDM2 protein inhibitors.17 cl, 1 dwg, 21 tbl, 360 ex
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Uesli</au><au>GKHOSH Partkha</au><au>BOLISETTI Ragkhu</au><au>VOSS Mettyu E</au><au>FRADERA LINAS Fransesk Ksaver</au><au>ALTMAN Majkl D</au><au>TOMPSON Kristofer Frensis</au><au>MARTINES Mishel</au><au>MASHASEK Mishell</au><au>KRISTOFER Mettyu P</au><au>SUN Binyuan</au><au>SIDZUKA Manami</au><au>TONI KURISSERI Antkhappan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS</title><date>2019-06-05</date><risdate>2019</risdate><abstract>FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and notably to specific imidazo[4,5-c]pyridine derivatives. Invention also relates to a pharmaceutical composition based on a specific imidazo[4,5-c]pyridine derivative useful in treating cancer.EFFECT: technical result is obtaining novel imidazopyridine derivatives useful as HDM2 protein inhibitors.17 cl, 1 dwg, 21 tbl, 360 ex
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS |
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