PROTEOLYTICALLY STABLE NONAPEPTIDE CAPABLE OF PREVENTING AN INCREASE IN HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM

FIELD: chemistry.SUBSTANCE: invention relates to a low-toxic, proteolytically stable, biologically active nonapeptide of formula H-Lys--Lys-Arg-Ala-Ala-Arg-Ala-Thr-Ser-NH(l). Claimed peptide can be used in medicine as a decongestant.EFFECT: claimed peptide is able to prevent the development of vascu...

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Hauptverfasser:	Ovchinnikov Mikhail Vladimirovich, Kazakova Olga Alekseevna, Shirinskij Vladimir Pavlovich, Samsonov Mikhail Vasilevich, Terekhova Olga Aleksandrovna, Khapchaev Asker Yusufovich, Sidorova Mariya Vladimirovna, Bushuev Valerij Nikolaevich, Palkeeva Marina Evgenevna, Azmuko Andrej Andreevich, Arzamastsev Evgenij Veniaminovich, Molokoedov Aleksandr Sergeevich
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: chemistry.SUBSTANCE: invention relates to a low-toxic, proteolytically stable, biologically active nonapeptide of formula H-Lys--Lys-Arg-Ala-Ala-Arg-Ala-Thr-Ser-NH(l). Claimed peptide can be used in medicine as a decongestant.EFFECT: claimed peptide is able to prevent the development of vascular hyperpermeability in stressful situations.1 cl, 4 dwg, 3 tbl, 5 ex Изобретение относится к малотоксичному, протеолитически устойчивому, биологически активному нонапептиду формулы, обладающему способностью предотвращать развитие сосудистой гиперпроницаемости в стрессовых ситуациях. Благодаря этому свойству заявляемый пептид может найти применение в медицине в качестве противоотечного средства. 4 ил., 3 табл., 5 пр.