METHOD FOR DETERMINATION OF THE DEGREE OF SEVERITY OF PSORIATIC ONYCHIA

FIELD: medicine.SUBSTANCE: invention relates to medicine, in particular to dermatovenereology, and is a method for determining the severity of psoriatic onychia, consisting in that the nail plates of brushes are treated with a mixture of diethyl ether-ethanol in a ratio of 1:1, are cut off, grinded,...

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Bibliographische Detailangaben
Hauptverfasser:	Evseev Andrej Viktorovich, Zirchik Anastasiya Anatolevna, Fedosov Evgenij Alekseevich, Azovskova Olga Vasilevna, Torshina Irina Evgenevna
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	FIELD: medicine.SUBSTANCE: invention relates to medicine, in particular to dermatovenereology, and is a method for determining the severity of psoriatic onychia, consisting in that the nail plates of brushes are treated with a mixture of diethyl ether-ethanol in a ratio of 1:1, are cut off, grinded, 30 mg of ground nail plates are extracted with a solution containing 5 ml of phosphate buffer with a pH of 7.4 and 1 ml of 96° ethyl alcohol, are maintained on a boiling water bath for 10 minutes, the mixture is filtered through a filter paper, then chemiluminescent analysis of the obtained extract is carried out to estimate the intensity of the fast flare (Fmax, rel.) and the light-weight sum of chemiluminescence (S, rel.), the coefficient Z equal to the ratio of S to Fmax is calculated, and at 7.04