NEW DERIVATIVE OF 3-(4-(BENZYLOXY)PHENYL)HEX-4-INE ACID, METHOD FOR ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION FOR METABOLIC DISEASE PREVENTION AND TREATMENT INCLUDING IT AS EFFECTIVE INGREDIENT

FIELD: pharmacology.SUBSTANCE: invention relates to a compound represented by formula 1, its optical isomer or a pharmaceutically acceptable salt thereof: [Formula 1], as well as to methods for its preparation and a pharmaceutical composition based on it.EFFECT: new connections are obtained, with th...

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Hauptverfasser:	YANG Dzin, KHA Tae-Yang, KIM Dzin Voong, LI Khan Kiu, RKHEE Dzaekeol, KIM Daekhoon, SON Chang Mo, KIM Dzae Khiun, LI Kiu Khvan, CHOI Khiung-Kho
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	FIELD: pharmacology.SUBSTANCE: invention relates to a compound represented by formula 1, its optical isomer or a pharmaceutically acceptable salt thereof: [Formula 1], as well as to methods for its preparation and a pharmaceutical composition based on it.EFFECT: new connections are obtained, with the ability to activate the GPR40 enzyme, suitable for use for metabolic disease prevention or treatment.10 cl, 7 tbl, 77 ex, 2 dwg Изобретение относится к соединению, представленному формулой 1, его оптическому изомеру или его фармацевтически приемлемой соли:[Формула 1], а также к способам его получения и фармацевтической композиции на его основе. Технический результат: получены новые соединения, обладающие способностью активировать фермент GPR40, пригодные для применения для профилактики или лечения метаболического заболевания. 7 н. и 3 з.п. ф-лы, 7 табл., 77 пр., 2 ил.