ETHYL ETHERS OF 2-AMINO-1-BENZOYLAMINO-4-OXO-5-(2-OXO-2-ARYL-ETHYLIDENE)-4,5-DIHYDRO-1H-PYRROLIDINE-3-CARBOXYLIC ACIDS, HAVING ANTI-TUMOUR ACTIVITY AND METHOD FOR PRODUCTION THEREOF

FIELD: chemistry.SUBSTANCE: invention relates to novel compounds of general formula Ia-d, where R=CHO (Ia), CHO (Ib), Br (Ic), Cl (Id), which have anticancer activity. Also disclosed is a method of producing compounds of formula Ia-d and their application for producing drug preparations for treating...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Ramazanov Bulat Rashitovich, Kiselev Maksim Aleksandrovich, Zykova Svetlana Sergeevna, Igidov Nazim Musabekovich, Odegova Tatyana Fedorovna, Semina Irina Ivanovna, Bojchuk Sergej Vasilevich, Galembikova Ajgul Rafikovna
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	FIELD: chemistry.SUBSTANCE: invention relates to novel compounds of general formula Ia-d, where R=CHO (Ia), CHO (Ib), Br (Ic), Cl (Id), which have anticancer activity. Also disclosed is a method of producing compounds of formula Ia-d and their application for producing drug preparations for treating oncological diseases.EFFECT: compounds exhibit low toxicity.3 cl, 4 dwg, 1 tbl, 6 ex Изобретение относится к новым соединениям общей формулы Iа-г, где R=СНO (Iа), СНO (Iб), Br (Iв), Cl (Iг), которые обладают противоопухолевой активностью. Также предложен способ получения соединений формулы Iа-г и их применение для получения лекарственных препаратов для лечения онкологических заболеваний. Соединения проявляют низкую токсичность. 3 н.п. ф-лы, 4 ил., 1 табл., 6 пр.