ANTIRETROVIRAL AGENTS BASED ON AZIDOTHYMIDINE DERIVATIVES

ANTIRETROVIRAL AGENTS BASED ON AZIDOTHYMIDINE DERIVATIVES

FIELD: chemistry.SUBSTANCE: invention relates to antiretroviral azidothymidine derivatives of formula 1 and can be used as a medicinal agent., where: R+R=-CH(CH)CH-, R+R=-CH(CH)CH-, R=H, R=CH, R=H, R=CHCHCH, R=H, R=C(CH), R=H, R=CH(CH)CH.EFFECT: novel effective agents with low toxicity against retro...

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Hauptverfasser: MARTYNOVA EKATERINA VLADIMIROVNA, PAVEL'EV ROMAN SERGEEVICH, RIZVANOV AL'BERT ANATOL'EVICH, SHTYRLIN JURIJ GRIGOR'EVICH, KHAJRULLINA REGINA RISHATOVNA
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:FIELD: chemistry.SUBSTANCE: invention relates to antiretroviral azidothymidine derivatives of formula 1 and can be used as a medicinal agent., where: R+R=-CH(CH)CH-, R+R=-CH(CH)CH-, R=H, R=CH, R=H, R=CHCHCH, R=H, R=C(CH), R=H, R=CH(CH)CH.EFFECT: novel effective agents with low toxicity against retroviral infections.16 ex, 2 tbl Изобретение относится к антиретровирусным производным азидотимидина формулы 1 и может быть использовано в качестве лекарственного средства., где:R+R=-CH(CH)CH-R+R=-CH(CH)CH-R=Н, R=СНR=H, R=CHCHCHR=H, R=C(CH)R=H, R=CH(CH)CHПредложены новые эффективные средства с низкой токсичностью против ретровирусных инфекций. 16 пр., 2 табл.