METHOD OF OBTAINING POTASSIUM LOSARTAN NANOCAPSULES

FIELD: chemistry.SUBSTANCE: potassium losartan is added by portions into a suspension of xanthane gum in benzene in the presence of the preparation E472 with mixing at 1000 rev/sec. Then hexane is added. The obtained suspension of nanocapsules is filtered and dried at room temperature. The envelope:...

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Hauptverfasser:	POKROVSKIJ MIKHAIL VLADIMIROVICH, KROLEVETS ALEKSANDR ALEKSANDROVICH, BOGACHEV IL'JA ALEKSANDROVICH, SOBOLEV MIKHAIL SERGEEVICH, JAKUSHEV VLADIMIR IVANOVICH, GUDYREV OLEG SERGEEVICH, REMIZOV PAVEL PAVLOVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	BABY COMFORTERS CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT THEREOF MEDICAL OR VETERINARY SCIENCE NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS NANOTECHNOLOGY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	FIELD: chemistry.SUBSTANCE: potassium losartan is added by portions into a suspension of xanthane gum in benzene in the presence of the preparation E472 with mixing at 1000 rev/sec. Then hexane is added. The obtained suspension of nanocapsules is filtered and dried at room temperature. The envelope:core ratio constitutes 3:1 or 1:5.EFFECT: simplification and acceleration of the process of obtaining nanocapsules and an increase of output by weight.2 ex Изобретение относится к способу получения нанокапсул лозартана калия в оболочке из ксантановой камеди. Согласно способу по изобретению лозартан калия добавляют по порциям в суспензию ксантановой камеди в бензоле в присутствии препарата Е472с при перемешивании 1000 об/сек. Затем приливают гексан. Полученную суспензию нанокапсул отфильтровывают и сушат при комнатной темепературе. Соотношение оболочка:ядро составляет 3:1 или 1:5. Способ по изобретению обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 2 пр.