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FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula:Iwhere (a) X is N or CR8; (b) R1 is H, F, Cl, Br; (c) R2 is H; (d) R3 is H, F, Cl, Br; (e) R4 is H, F, Cl, Br, I, CN, substituted or unsubstituted C-Calkyl, substituted or unsubstituted C-Calkenyl, substituted or unsubstituted C-...
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Sprache: | eng ; rus |
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Zusammenfassung: | FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula:Iwhere (a) X is N or CR8; (b) R1 is H, F, Cl, Br; (c) R2 is H; (d) R3 is H, F, Cl, Br; (e) R4 is H, F, Cl, Br, I, CN, substituted or unsubstituted C-Calkyl, substituted or unsubstituted C-Calkenyl, substituted or unsubstituted C-aryl, SR9, where each of said R4, which is substituted, contains one or more substitutes selected from F, Cl, Br; (f) R5 is H, substituted or unsubstituted C-Calkyl, substituted or unsubstituted C-Calkenyl, C(=X1)R9, C(=X1)OR9, C-CalkylC-aryl (where the aryl can be substituted or unsubstituted), R9X2C(=X1)R9, R9X2R9, C(=O)(C-Calkyl)S(O)(C-Calkyl), C(=O)(C-Calkyl)C(=O)O(C-Calkyl), (C-Calkenyl)C(=O)O(C-Calkyl), SR9, R9S(O)R9; where each of said R5, which is substituted, contains one substitute selected from F, Cl, Br, C-Ccycloalkyl, OR9, optionally, R5 and R7 can be bonded to form a Ccyclic system; (g) R6 is O, S, NR9; (h) R7 is substituted or unsubstituted C-Calkyl, substituted or unsubstituted C-Calkenyl, substituted or unsubstituted C-Calkoxy, substituted or unsubstituted C-Ccycloalkyl, substituted or unsubstituted C-aryl, substituted or unsubstituted C-Cheterocyclyl, selected from thiazole, oxazole, isothiazole, thiophene, pyrroidine, furan, tetrahydrothiophene, pyridazine, piperdine, pyrazole, OR9, OR9S(O)R9, C(=X1)R9, R9C(=X1)OR9, N(R9), N(R9)(R9S(O)R9), SR9, R9S(O)R9, C-CalkylC-Cheterocyclyl (where the heterocyclyl is selected from triazole and pyrazole), C-CalkylS(=N-CN)(C-Calkyl), C-CalkylS(O)(=N-CN)(C-Calkyl), C-CalkylNH(C(=O)OC-Calkyl), C-CalkylC(=O)OC-Calkyl, C-Calkyl(C-aryl)NH(C(=O)OC-Calkyl), C-Calkyl(S-C-Calkyl)NH(C(=O)OC-Calkyl), C-Calkyl(S-C-Calkyl-C-aryl)NH(C(=O)OC-Calkyl), C-Calkyl(NHC(=O)OC-CalkylC-aryl)NH(C(=O)OC-Calkyl), C-Calkyl(OC-CalkylC-Caryl)NH(C(=O)OC-Calkyl), C-CalkylNH(C-Calkyl)(C(=O)OC-Calkyl), C-CalkylNH(C-Calkyl), C-CalkylN(C-Calkyl)(S(O)C-Calkyl), C-CalkylN(C-Calkyl)(S(O)C-CalkenylC-aryl), C-CalkylN(C-Calkyl)(C(=O)C-Cheterocyclyl) (where the heterocyclyl is selected from pyrazole or thiophene), C-CalkylN(C-Calkyl)(C(=O)OC-CalkylC-aryl), NH(C-CalkylS(O)C-Calkyl), where each of said R7, which is substituted, contains one or more substitutes selected from F, Cl, Br, C-Calkyl, C-Ccycloalkyl, C(=X1)R9, C(=X1)OR9, =X2, S(=X2)R9; (i) R8 is H, F, Cl, Br, I, CN, unsubstituted C-Calkoxy, C(=X)OR9, S(O)R9; (j) R9 (each independently) is H, substituted or unsubstituted C-Calkyl, substituted or unsubstituted C-Calkenyl, substituted or unsubsti |
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