CD138-TARGETED CELL AGENTS AND USING THEM

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to biotechnology and immunology. What is presented is a genetically engineered antibody able to bind human CD138. There are described its heavy and light chain sequences, as well as their CDR.EFFECT: presented antibody can be used as an ingr...

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Bibliographische Detailangaben
Hauptverfasser:	GERMER,MATTIAS, SHUL'TS,GREGOR, AJGNER,ZIL'KE, TSENG,SHTEFFEN, OSTERROT,FRANK, DELKEN,BENZHAMIN, BRJUKHER,KRISTOF, UEHREK,KRISTOF, KRAUS,EHL'MAR
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to biotechnology and immunology. What is presented is a genetically engineered antibody able to bind human CD138. There are described its heavy and light chain sequences, as well as their CDR.EFFECT: presented antibody can be used as an ingredient of a pharmaceutical composition for treating tumours.13 cl, 21 dwg, 5 tbl Изобретение относится к области биотехнологии и иммунологии. Предложено генетически созданное антитело, способное связывать CD138 человека. Описаны последовательности его тяжелой и легкой цепей, а также их CDR. Предложенное антитело может быть использовано, в составе фармацевтической композиции, для лечения опухолей. 6 н. и 7 з.п. ф-лы, 21 ил., 5 табл.