DIAGNOSTIC TECHNIQUE FOR UROLITHIASIS

FIELD: medicine.SUBSTANCE: original urine sample is divided into two equal samples; particle size histogram is prepared and used to find a percentage of an oligomer form of Tamm-Horsfall protein T&HE(7); the sample histograms are compared. A Tamm-Horsfall protein identification protein is presen...

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Hauptverfasser:	GOLOSHCHAPOV EVGENIJ TIKHONOVICH, EHMANUEHL' JULIJA VLADIMIROVNA, AL'-SHUKRI SAL'MAN KHASUNOVICH, LANDA SERGEJ BORISOVICH, GORBACHEV MIKHAIL IGOREVICH, EHMANUEHL' VLADIMIR LEONIDOVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	FIELD: medicine.SUBSTANCE: original urine sample is divided into two equal samples; particle size histogram is prepared and used to find a percentage of an oligomer form of Tamm-Horsfall protein T&HE(7); the sample histograms are compared. A Tamm-Horsfall protein identification protein is presented by monoclonal antibodies undergoing an immune-affine reaction with Tamm-Horsfall protein. The second sample is used to recover Tamm-Horsfall protein T&HE(28); and both urine samples are used to measure the oligomer form of Tamm-Horsfall protein T&HE(28) in the free condition and in aggregates with oxalate microcrystals (%). The relation of the derived oligomer forms is calculated by formulas: C1=T&HE(28)A/T&HE(7) and C2=T&HE(28)F/T&HE(7). If observing C1>1.5 and any C2, urolithiasis is diagnosed; the relations C1