HYDROBENZAMIDE DERIVATIVES AS Hsp90 INHIBITORS

FIELD: chemistry.SUBSTANCE: invention relates to an acid addition salt of a compound of formula(1), formed by L-lactic acid. The compound (1) can be used as a Hsp90 inhibitor. Described are methods of producing a compound of formula (1), intermediate compounds used to produce a compound of formula (...

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Hauptverfasser:	VINKOVICH MLADEN, VUDKHED EHNDRJU DZHEJMS, VILL'JAMS BRAJAN, LAJONS DZHON FREHNSIS, VULFORD EHLISON DZHO-EHNN, FREDERIKSON MARTIN, TOMPSON NIL TOMAS
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: chemistry.SUBSTANCE: invention relates to an acid addition salt of a compound of formula(1), formed by L-lactic acid. The compound (1) can be used as a Hsp90 inhibitor. Described are methods of producing a compound of formula (1), intermediate compounds used to produce a compound of formula (1) and methods of producing the intermediate compounds.EFFECT: obtaining an acid addition salt of a compound of formula (1), formed by L-lactic acid.10 cl, 22 dwg, 4 dwg, 22 tbl, 12 ex Изобретение относится к кислотно-аддитивной соли соединения формулы (1),образованная L-молочной кислотой. Соединение (1) может быть использовано в качестве ингибитора Hsp90. Описаны способы получения соединения формулы (1), промежуточные соединения, используемые для получения соединения (1), способы получения промежуточных соединений. 8 н. и 2 з.п. ф-лы, 22 ил., 4 схемы, 22 табл., 12 пр.