METHOD OF DETERMINING PRESENCE OF ANTHRAX PROTECTIVE ANTIGEN BASED ON IMMUNODETECTION, ASSOCIATED WITH POLYMERASE CHAIN REACTION

FIELD: medicine.SUBSTANCE: invention relates to field of biotechnology, medical biochemistry, diagnostic medical microbiology, applied immunochemistry and development of diagnostic test-systems. Elaborated is novel method of determining anthrax protective antigen, based on immumodetection, associate...

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Hauptverfasser:	KOLESNIKOV ALEKSANDR VLADIMIROVICH, SHEMJAKIN IGOR' GEORGIEVICH, BELOVA ELENA VALENTINOVNA, KOZYR' ARINA VLADIMIROVNA, KHLYNTSEVA ANNA EVGEN'EVNA
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Zusammenfassung:	FIELD: medicine.SUBSTANCE: invention relates to field of biotechnology, medical biochemistry, diagnostic medical microbiology, applied immunochemistry and development of diagnostic test-systems. Elaborated is novel method of determining anthrax protective antigen, based on immumodetection, associated with polymerase chain reaction.EFFECT: method possesses high sensitivity and specificity, which make it possible to carry out fast diagnostics of accumulation of anthrax protective antigen protein at early stages of infection.5 dwg, 4 ex Изобретение относится к области биотехнологии, медицинской биохимии, диагностической медицинской микробиологии, прикладной иммунохимии и разработке диагностических тест-систем. Разработан новый способ определения протективного антигена сибирской язвы на основе иммунодетекции, сопряженной с полимеразной цепной реакцией. Способ обладает высокой чувствительностью и специфичностью, позволяющими быстро провести диагностику накопления белка протективного антигена сибирской язвы на ранних стадиях инфекции. 5 ил., 4 пр.