PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DIABETES MELLITUS AND OBESITY CONTAINING COMPOUND INHIBITING ACTIVITY OF DIPEPTIDYLPEPTIDASE-IV, AND OTHER ANTIDIABETIC AGENTS OR ANTIOBESITY AGENTS AS ACTIVE INGREDIENTS

PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DIABETES MELLITUS AND OBESITY CONTAINING COMPOUND INHIBITING ACTIVITY OF DIPEPTIDYLPEPTIDASE-IV, AND OTHER ANTIDIABETIC AGENTS OR ANTIOBESITY AGENTS AS ACTIVE INGREDIENTS

FIELD: medicine. ^ SUBSTANCE: invention refers to a pharmaceutical composition for prevention and treatment of diabetes mellitus and obesity containing as active ingredients a compound inhibiting activity of dipeptidylpeptidase-IV (DPP-IV), its pharmaceutically acceptable salt, its hydrate or its so...

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Hauptverfasser: SON MOON-KHO, JOO MOOKHI, KIM SOON KHOE, SHIN CHANG JELL, CHOI SONG-KHIEN, MIN DZONG PIL, JOON TAE KHIUN, KIM KHEUNG-DZAE, JANG EUN KIOUNG, KVAK VOO JANG, CHAE JU NA, AKHN GOOK-DZUN
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:FIELD: medicine. ^ SUBSTANCE: invention refers to a pharmaceutical composition for prevention and treatment of diabetes mellitus and obesity containing as active ingredients a compound inhibiting activity of dipeptidylpeptidase-IV (DPP-IV), its pharmaceutically acceptable salt, its hydrate or its solvate, and one or more other antidiabetic agents or antiobesity agents. ^ EFFECT: pharmaceutical composition shows excellent improvement of glucose tolerance and may be used in prevention and treatment of diabetes mellitus, obesity and similar diseases, effectively reducing blood glucose level and weight. ^ 25 cl, 8 dwg, 17 tbl, 32 ex Настоящее изобретение относится к фармацевтической композиции для профилактики и лечения диабета или ожирения, содержащей в качестве активных ингредиентов соединение, ингибирующее активность дипептидилпептидазы-IV (ДПП-IV), его фармацевтически приемлемую соль, его гидрат или его сольват, и одно или несколько других противодиабетических средств или средства против ожирения. Фармацевтическая композиция демонстрирует превосходное улучшение толерантности к глюкозе и может быть использована в профилактике и лечении диабета, ожирения и подобных заболеваний, эффективно снижая уровни глюкозы в крови и снижая жировую массу. 24 з.п. ф-лы, 8 ил., 17 табл., 32 пр.