PHARMACEUTICAL COMPOUNDS

FIELD: chemistry. ^ SUBSTANCE: invention relates to compounds of formulae ^ and , ^ which can be used to inhibit lipid kinase, including PI3K, and treat lipid kinase-mediated disorders. Values of radicals are given in claim 1. ^ EFFECT: improved properties of the compound. ^ 11 cl, 2 tbl, 7 ex Изобр...

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Hauptverfasser:	GANZNER DZHENET, KHEFFRON TIM, SHATTLVORT STEFEN, CHZHU BIN-JAN, FOLKS EHDRIAN, OLIVERO ALAN, MAT'E SIMON, CHAKOVRI IRINA, SAZERLIN DEHNIEL' P, VAN NAN CHI, KASTANEDO DZHORDZHETTA, OKSENFORD SALLI, GOLDSMIT RICHARD
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: chemistry. ^ SUBSTANCE: invention relates to compounds of formulae ^ and , ^ which can be used to inhibit lipid kinase, including PI3K, and treat lipid kinase-mediated disorders. Values of radicals are given in claim 1. ^ EFFECT: improved properties of the compound. ^ 11 cl, 2 tbl, 7 ex Изобретение относится к соединениям формул Ia и Ib ! ! которые полезны для ингибирования липидкиназ, включая ФИЗК, и для лечения расстройств, опосредованных липидкиназами. Значения радикалов представлены в п.1 формулы изобретения. 3 н. и 8 з.п. ф-лы., 2 табл.