CARBAMOYL BENZOTRIAZOLE DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS

CARBAMOYL BENZOTRIAZOLE DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS

FIELD: chemistry. ^ SUBSTANCE: invention describes novel carbamoyl benzotriazole derivatives of general formula , (values of radicals are given in the description), tautomers thereof and pharmaceutically acceptable salts and use thereof as endothelial lipase inhibitors. ^ EFFECT: improved properties...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TSOLLER GERKHARD, MJULLER GJUNTER, TENNAGEL'S NORBERT, PETRI SHTEFAN
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:FIELD: chemistry. ^ SUBSTANCE: invention describes novel carbamoyl benzotriazole derivatives of general formula , (values of radicals are given in the description), tautomers thereof and pharmaceutically acceptable salts and use thereof as endothelial lipase inhibitors. ^ EFFECT: improved properties of the derivatives. ^ 11 cl, 148 ex Описываются новые производные карбамоилбензотриазола общей формулы (I), ! ! (значения радикалов приведены в описании), их таутомеры и фармацевтически приемлемые соли и применение их в качестве ингибиторов эндотелиальной липазы. 6 н. и 5 з.п. ф-лы.