SULPHUR-CONTAINING COMPOUNDS AS HEPATITIS C VIRUS NS3 SERINE PROTEASE INHIBITORS

FIELD: chemistry. ^ SUBSTANCE: invention relates to novel compounds with HCV protease inhibiting activity, as well as methods for synthesis of such compounds. In another version, the invention relates to pharmaceutical compositions containing said compounds, as well as methods of using said compound...

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Hauptverfasser:	LIU JI-TSUNG, CHEN KEVIN KS, LOUVI REJMOND DZH, VENKATRAMAN SRIKANT, ARASAPPAN ASHOK, BOUDZHEN STEFANI L, SANNIGRAKHI MUSUMI, VELASKES FRANTSISKO, NJOROGE F. DZHORDZH, GIRIJAVALLABKHAN VIJUR M, KHUANG JUKHUA, NAIR LATKHA, SAKSENA ANIL K, BENNETT FREHNK, KHENDRATA SISKA
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: chemistry. ^ SUBSTANCE: invention relates to novel compounds with HCV protease inhibiting activity, as well as methods for synthesis of such compounds. In another version, the invention relates to pharmaceutical compositions containing said compounds, as well as methods of using said compounds to treat disorders associated with HCV protease. ^ EFFECT: high inhibiting activity of compounds. ^ 48 cl, 5 tbl, 833 ex Настоящее изобретение относится к новым соединениям, обладающим ингибирующей активностью в отношении протеазы HCV, равно как и к способам получения таких соединений. В другом варианте выполнения изобретение относится к фармацевтическим композициям, содержащим такие соединения, равно как и к способам их применения для лечения нарушений, связанных с протеазой HCV. 10 н. и 38 з.п. ф-лы, 5 табл.