NOVEL PEPTIDES AS INHIBITORS OF HEPATITIS C VIRUS NS3-SERINE PROTEASE

FIELD: medicine. ^ SUBSTANCE: invention relates to novel peptide compounds, which possess ability to inhibit protease of hepatitis C virus (HCV), their pharmaceutical compositions and application of compounds for obtaining medication for diseases associated with HCV. ^ EFFECT: improvement of compoun...

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Hauptverfasser: CHEN KEVIN KS, KHENDREHJTA SISKA, CHAN TIN-JAU, BOUDZHEN STEFANI L, LIU JU-TSUNG, EHRESEPPEN EHSHOK, GIRIJAVALLABKHN VIJJUR M, SAKSENA EHNIL K, BENNETT FRENK, ZHU ZHAONING, VEKKEJRO KHENRI A, VONG DZHESSI K, JAO EHDVIN, PINTO PATRIK A, KHUANG JUKHUA, LAVI REJMOND DZH, NIOROUDZH DZHORDZH F, VU VANLI, NEJR LETA DZH, PAJK RASSEL I, KEMP SKOTT DZHEFRI, MAK KORMIK DZHINPING L, GENGJULI EHSHIT K, VENKETREMEN SRIKENT, LEVI ODAJL EHSTER, VANG KHEJJAN, PERIK TIJAL, LIM-UILBI MARGARIT, TEJMURA S'JUZAN I, SENTKHENEM BAMA
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Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine. ^ SUBSTANCE: invention relates to novel peptide compounds, which possess ability to inhibit protease of hepatitis C virus (HCV), their pharmaceutical compositions and application of compounds for obtaining medication for diseases associated with HCV. ^ EFFECT: improvement of compound properties. ^ 48 cl, 6 tbl, 65 ex Изобретение относится к новым пептидным соединениям, которые обладают способностью ингибировать протеазу вируса гепатита С (HCV), их фармацевтическим композициям и применению соединений для получения лекарственного средства для лечения заболеваний, связанных с HCV. 10 н.и 38 з.п. ф-лы, 6 таб.