NONAPEPTIDE AMIDE, POSSESSING ABILITY TO PREVENT INCREASE OF VESSEL ENDOTHELIUM PERMEABILITY

FIELD: medicine. ^ SUBSTANCE: invention relates to biologically active peptides, able to prevent sharp increase of permeability of vessel endothelium. Claimed is peptide of formula H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 and its pharmaceutically acceptable salts. ^ EFFECT: peptide can be ap...

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Hauptverfasser:	SEKRIDOVA ALEKSANDRA VLADIMIROVNA, BESPALOVA ZHANNA DMITRIEVNA, KULIKOVA TAT'JANA GAVRIILOVNA, MARCHENKO ALEKSEJ VASIL'EVICH, STEPANOVA OL'GA VLADISLAVNA, SHIRINSKIJ VLADIMIR PAVLOVICH, SIDOROVA MARIJA VLADIMIROVNA, BUSHUEV VALERIJ NIKOLAEVICH, MOLOKOEDOV ALEKSANDR SERGEEVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine. ^ SUBSTANCE: invention relates to biologically active peptides, able to prevent sharp increase of permeability of vessel endothelium. Claimed is peptide of formula H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 and its pharmaceutically acceptable salts. ^ EFFECT: peptide can be applied as anti-edema medication in various fields of medicine. ^ 1 dwg, 2 ex Изобретение относится к биологически активным пептидам, способным предотвращать острое повышение проницаемости сосудистого эндотелия. Предложен пептид формулы H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 и его фармацевтически приемлемые соли. Заявленный пептид может найти применение в качестве противоотечного средства в различных областях медицины (в кардиологии, токсикологии, нейрохирургии и др.). 1 ил., 1 табл.