HYDRAZONES OF AZIDOKETONES OF ALICYCLIC AND ALIPHATIC RANGE, HAVING ANTIVIRAL ACTIVITY

FIELD: medicine. ^ SUBSTANCE: invention is related to new hydrazones of azidoketones of alicyclic and aliphatic range, having activity against orthopoviruses, with common formula , where R1=1-Ad, R2=3-R-1-Ad (R=OH, 4-tolyl), 2-Ad, H, 4-tolyl, 4-bromine-phenyl, 4-hydroxyphenyl, 4-methoxyphenyl; R1=3-...

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Hauptverfasser:	MOISEEV IGOR' KONSTANTINOVICH, MATVEEV ALEKSANDR IVANOVICH, KLIMOCHKIN JURIJ NIKOLAEVICH, LEONOVA MARINA VALENTINOVNA, BORMOTOV NIKOLAJ IVANOVICH, SEROVA OL'GA ALEKSEEVNA, GOLOVIN EVGENIJ VALER'EVICH, BALAKHNIN SERGEJ MARKOVICH, BELANOV EVGENIJ FEDOROVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine. ^ SUBSTANCE: invention is related to new hydrazones of azidoketones of alicyclic and aliphatic range, having activity against orthopoviruses, with common formula , where R1=1-Ad, R2=3-R-1-Ad (R=OH, 4-tolyl), 2-Ad, H, 4-tolyl, 4-bromine-phenyl, 4-hydroxyphenyl, 4-methoxyphenyl; R1=3-Br-1-Ad, R2=1-Ad, NH2; R1=tretbutyl, R2=1-Ad, where Ad-adamantyl. ^ EFFECT: increased antiviral activity of compounds. ^ 8 tbl, 12 ex Изобретение относится к новым гидразонам азидокетонов алициклического и алифатического ряда, обладающим активностью против ортопоксвирусов, общей формулы ! ! где R1=1-Ad, R2=3-R-1-Ad (R=OH, 4-толил), 2-Ad, Н, 4-толил, 4-бромфенил, 4-гидроксифенил, 4-метоксифенил; R1=3-Br-1-Ad, R2=1-Ad, NH2; R1=третбутил, R2=1-Ad, где Ad - адамантил. 8 табл.