NEW ISOINDOLE DERIVATIVES, COMPOSITIONS CONTAINING THEREOF, PRODUCTION AND PHARMACEUTICAL APPLICATION THEREOF, PARTICULARLY AS INHIBITORS OF CHAPERONE PROTEIN Hsp90 ACTIVITY

FIELD: medicine. ^ SUBSTANCE: there are described new isoindole derivatives of general formula (1), wherein A1, A2 and A4 stands for CH, and A3 means N or C-OH; n is equal to 2; R1 represents O; R2-stands for H; and a pharmaceutical composition containing thereof. ^ EFFECT: new compounds are inhibit...

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Hauptverfasser:	BERTEHN LJUK, VALLE FRANSUA, KARRE SHANTAL, MAJLIE PATRIK, BAK EHRIK, BENAR DID'E
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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