REMEDY HAVING ANTIAGGREGANT ACTIVITY, ACTIVITY DECREASING BLOOD HYPERVISCOSITY AND ANTITHROMBOGENIC ACTIVITY

FIELD: medicine . ^ SUBSTANCE: invention refers to medicine and namely to pharmacology and deals with remedies influencing free-radical processes, hemorheology, thrombocyte aggregation and intravascular thrombosis. It has been proposed to use (3,5-dimethyl-4- hydroxy)benzyl thiododecane which is kno...

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Hauptverfasser:	IVANOV IVAN SERGEEVICH, CHERNYSHEVA GALINA ANATOL'EVNA, BOJKO MARINA ALEKSANDROVNA, SMOL'JAKOVA VERA IVANOVNA, PLOTNIKOV MARK BORISOVICH, GROSS MIKHAIL ALEKSANDROVICH, PROSENKO ALEKSANDR EVGEN'EVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	FIELD: medicine . ^ SUBSTANCE: invention refers to medicine and namely to pharmacology and deals with remedies influencing free-radical processes, hemorheology, thrombocyte aggregation and intravascular thrombosis. It has been proposed to use (3,5-dimethyl-4- hydroxy)benzyl thiododecane which is known for its antioxidant activity as antiaggregant remedy decreasing blood hyperviscosity, and antithrombogenic remedy. ^ EFFECT: there has been shown the stated effectiveness of the remedy by means of blood hyperviscosity pattern and increase of blood flow under conditions of its complete stop when there are no thrombs in arteria the next day. ^ 4 tbl, 14 ex Изобретение относится к медицине, конкретно к фармакологии, и касается средств, влияющих на свободнорадикальные процессы, реологию крови, агрегацию тромбоцитов и внутрисосудистое тромбообразование. Предложено использование (3,5-диметил-4-гидрокси)бензилтиододекана, известного антиоксидантной активностью, в качестве антиагрегантного, уменьшающего повышенную вязкость крови и антитромбогенного средства. Показана заявленная эффективность средства на модели гипервязкости крови и повышение кровотока в условиях его полной остановки при отсутствии тромбов а артерии на следующие сутки. 4 табл.