DIAMINOTRIAZOLES, SUITABLE AS INHIBITORS OF PROTEIN KINASES

FIELD: medicine. ^ SUBSTANCE: formula bond ^ or it pharmaceutically comprehensible salt where value of radicals are specified in the invention formula is described. The bonds are effective as inhibitors of protein kinases FLT-3 or KIT. A way of inhibition of activity kinases FLT-3 or KIT in the biol...

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Bibliographische Detailangaben
Hauptverfasser:	MESSERSMIT DEHVID, SJUJ TSZIN'VAN, LEDFORD BRAJAN, NANTAKUMAR SUGANTI, PIRS AL'BERT K, SALITURO FRANCHESKO G, GREJ RONAL'D, FORSTER KORNELIJA DZH, DZHAJARADZH EHNDRJU, KHENKEL GREHG, DEHVIS ROBERT DZH, BINCH KHEHJLI, EHRNOST MAJKL, LEDEBUR MARK, TJAN' SHI-KAJ, GALULLO VINSENT, VAN TSZJAN
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine. ^ SUBSTANCE: formula bond ^ or it pharmaceutically comprehensible salt where value of radicals are specified in the invention formula is described. The bonds are effective as inhibitors of protein kinases FLT-3 or KIT. A way of inhibition of activity kinases FLT-3 or KIT in the biological sample in vitro and application of bonds for manufacture of a medical product, suitable for treatment or simplification of gravity of disease or a condition, the chosen acute myelogenetic leukosis, acute progranulocytic leukemia or acute lymphocytic leukosis or cancer of ovaries are described also. ^ EFFECT: rising of efficiency of a composition and the method of treatment. ^ 11 cl, 86 ex