OXALIPLATIN WITH LOW CONTENT OF ACCOMPANYING ADMIXTURES AND METHOD OF OBTAINING IT

OXALIPLATIN WITH LOW CONTENT OF ACCOMPANYING ADMIXTURES AND METHOD OF OBTAINING IT

FIELD: chemistry. ^ SUBSTANCE: claimed invention relates to obtaining oxaliplatin used in tumor treatment, with low content of accompanying admixtures formed while obtaining it. Obtained is oxaliplatin with wt % content of admixtures of alkali metals not more than 0.01%, silver not more than 0.0005%...

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Bibliographische Detailangaben
Hauptverfasser: ZHAK FRANTISHEK, CHAJKA-POULOVA ANNA
Format: Patent
Sprache:eng ; rus
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:FIELD: chemistry. ^ SUBSTANCE: claimed invention relates to obtaining oxaliplatin used in tumor treatment, with low content of accompanying admixtures formed while obtaining it. Obtained is oxaliplatin with wt % content of admixtures of alkali metals not more than 0.01%, silver not more than 0.0005% and nitrates not more than 0.01%. Method of obtaining lies in the following: suspension of (SP-4-2)-dichloro-[(1R,2R)-1,2-cyclohexanediamine-N,N'] platinum (II) in water is processed with silver nitrate with molar ratio of complex compound to silver nitrate 1: