METHOD OF PREDICTING FASTNESS OF MEMBRANES OF PERIPHERIC BLOOD ERYTHROCYTES AT EXACERBATION OF HERPESVIRUS INFECTION AT PREGNANT WOMEN

FIELD: medicine. ^ SUBSTANCE: method of prediction of fastness of membranes of erythrocytes of peripheric blood at an exacerbation of herpesvirus infection at pregnant women is characterised that on silica gel by means of two-dimensional, a thin-layer chromatography is defined in phospholipid struct...

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Hauptverfasser: ANDRIEVSKAJA IRINA ANATOL'EVNA, LUTSENKO MIKHAIL TIMOFEEVICH
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine. ^ SUBSTANCE: method of prediction of fastness of membranes of erythrocytes of peripheric blood at an exacerbation of herpesvirus infection at pregnant women is characterised that on silica gel by means of two-dimensional, a thin-layer chromatography is defined in phospholipid structure of membranes of erythrocytes the content of lysophosphatidilcholine, simultaneously same portion of blood in membranes of erythrocytes a method an electrophoresis disk in step gradient 10% polyacrylamide gel with sodium dodecyl sulfate define the content of protein of a strip 3, an integrated estimation of interrelation between investigated parametres at healthy pregnant women and the pregnant women who have tested an exacerbation herpes-virus of an infection, solve, defining discriminant function (D), by means of the discriminant equation under formula D=7/36xLph+{-6.216 x a protein of a strip 3}, and at value D peer or less than -12.8 prognosticate instability of membranes of erythrocytes. ^ EFFECT: augmentation of lysophosphatidilcholine in membranes of erythrocytes of peripheric blood depending on change of a protein of a strip 3 at exacerbation of herpes-virus infection at pregnant women. ^ 1 ex, 1 dwg