PREPARATION CONTAINING ANTIBODY AGAINST BOLIVIAN HAEMORRAGIC FEVER FROM WHEY OF BLOOD OF HORSES, SOLUTION FOR INTRAMUSCULAR INTRODUCTION

FIELD: medicine; pharmacology. ^ SUBSTANCE: essence of the invention includes a 9.0-11.0% solution of an antibody for the intramuscular introduction, possessing virus neutralising activity to Machupo virus, obtained from hyperimmune whey of the horses, containing scale-globulin fraction in amount no...

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Hauptverfasser: PANTJUKHOV VLADIMIR BORISOVICH, SYROMJATNIKOVA SVETLANA IVANOVNA, KHMELEV ALEKSEJ LEONIDOVICH, SHATOKHINA IRINA VIKTOROVNA, MEL'NIKOV SERGEJ ALEKSEEVICH, PIROZHKOV ALEKSEJ PETROVICH, SHAGAROV EVGENIJ EVGEN'EVICH, POTRYVAEVA NEHLLI VASIL'EVNA
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Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine; pharmacology. ^ SUBSTANCE: essence of the invention includes a 9.0-11.0% solution of an antibody for the intramuscular introduction, possessing virus neutralising activity to Machupo virus, obtained from hyperimmune whey of the horses, containing scale-globulin fraction in amount not less than 85.0%, and as nonspecific impurity - albumine, the alpha and beta-globulin fractions in amount not more than 15.0% residual ethyl spirit in amount not more than 4.5%, having pH from 7.0 to 7.5 and a titre of the virus-neutralising antibodies not less 1:1024 of fever; the preparation contains albumine, alpha- and beta-globulin fractions in amount not more than 15.0% and residual ethyl spirit in amount not more than 4.5%. ^ EFFECT: working out of a preparation for emergency prevention of Bolivian haemorragic fever. ^ 1 ex, 1 tbl