ACIDYLATED HETEROARYLCONDENSED CYCLOALKENYLAMINES AND THEIR USE AS PHARMACEUTICAL AGENTS

FIELD: chemistry. ^ SUBSTANCE: invention pertains to acidylated heteroarylcondensed cycloalkenylamines with formula I in any of their stereoisomeric form or in form of their mixtures in any ratio, or their pharmaceutical salts, where in formula I: ring A represents an aromatic 6-member ring, containing 1 nitrogen atom, or a 5-member aromatic ring, containing 1 sulphur atom; one or two of R1, R2, R3 and R4 is independently chosen from a group consisting of hydrogen, halogen or C1-C4-alkyl, and the other R1, R2, R3 and R4 represent hydrogen; R5 represents an Ar group or Hetar group. Description is also given of a pharmaceutical composition based on compound with formula I and use of the latter. ^ EFFECT: regulation of the expression of the enzyme endothelial NO-synthesis. ^ 10 cl, 31 ex